Treatment of Haemophilia with Dried Human Fibrinogen
نویسندگان
چکیده
The coagulation curve obtained by the technique previously reported by the authors has been recently interpreted by J. B. Graham and E. M. Barrow as explainable to a large extent by a variation of the ionic force of the medium during dilution. In order to overcome the influence of this physico-chemical factor and to reveal the action of the biological coagulation factors, the authors have performed dilution experiments at a constant ionic force, and at a constant citric ion content. Furthermore, the coagulation-dilution test makes it possible to display, both in normal and hemophilic blood, a certain number of factors whose action is discussed.
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